Orfiril, solution for injection is intended for patients being treated with sodium valproate and for whom oral administration of sodium valproate is temporarily not possible, for the treatment of:
The primary form of generalized epilepsy:
typical and atypical absence seizures (petit mal)
myoclonus
tonic-clonic seizures (grand mal)
mixed forms of tonic-clonic seizures and absence seizures
May also be used for manifestations of epilepsy that do not respond adequately to other antiepileptic drugs, such as:
the secondary form of generalized epilepsy, particularly akinetic and atonic seizures
partial epilepsy, with both simple (focal) and complex (psychomotor) symptoms
Treatment of manic episodes in bipolar disorder when lithium is contraindicated or not tolerated.
Orfiril 100 mg/ml contains 100 mg of sodium valproate per ml of solution for injection. In the Netherlands, Orfiril 100 mg/ml is supplied in packs of 5 ampoules, each containing 3 ml.
Orfiril, solution for injection, is a prescription-only medicine and is distributed by TwinPharma BV. Desitin Arzneimittel GmbH is the marketing authorisation holder.